The Center for Cellular Biointerfaces in Science and Engineering (CCBSE) is co-led by NDSU University Distinguished Professor Kalpana S. Katti, Ph.D., F. AIMBE and UND Chester Fritz Distinguished Professor of Chemistry and Associate Dean for Research Mark Hoffmann. The CCBSE has three pillars of scientific inquiry: materials design at biointerfaces; cellular systems at materials interface; and computation, machine learning, and predictive modeling.
The CCBSE is supported by ND-ACES: New Discoveries in the Advanced Interface of Computation, Engineering, and Science, ND EPSCoR’s most recent NSF cooperative agreement (award number 1946202), and is a five-year cooperative agreement that carries an 80/20% federal/state match.
The ND-ACES Principal Investigator (PI) and Project Director (PD) is Colleen Fitzgerald, Ph.D.; NDSU. The Co-PI is John Mihelich, Ph.D.; UND.
Center for Cellular Biointerfaces in Science and Engineering Leadership
Mark Hoffmann
Mark Hoffmann is a UND Chester Fritz Distinguished Professor of Chemistry and Associate Dean for Research, University of North Dakota. Contact Mark Hoffmann.
Kalpana S. Katti
Kalpana Katti is a University Distinguished Professor in the Department of Civil, Construction and Environmental Engineering and the Graduate Program Coordinator at North Dakota State University. Contact Kalpana S. Katti
Publications
View a complete list of student and faculty publications here. Publications can also be found in the NSF Public Access Repository (NSF-PAR)
Materials Design at Biointerfaces Pillar
The Materials Design at Biointerfaces Pillar objective is to progressively increase CCBSE researcher knowledge and application in the area of biomaterial scaffolds relevant to tissue engineering, particularly in the area of design methodologies of biologically inspired materials for diverse 3D tissue architectures. This pillar is co-led by Sanku Mallik (NDSU) and Julia Xiaojun Zhao (UND).
Cellular Systems at Materials Interface Pillar
The Cellular Systems at Materials Interface Pillar objective is to increase the capacity and expertise of the CCBSE researchers in basic and translational use of in vivo-like 3D cell cultures, which will ultimately (long-term outcome) allow the team to partner with regional health care providers to serve as a resource for personalized medicine approaches to cancer. This pillar is co-led by Archana Dhasarathy (UND) and John C. Wilkinson (NDSU).
Computation, Machine Learning, and Predictive Modeling Pillar
The Computation, Machine Learning, and Predictive Modeling Pillar objective is to enhance connected learning, knowledge, and application across multi-scale modeling, machine learning platforms, and experimental biomaterials and cellular data, which will result in an evolutionary in-silico platform to predict tumor growth. Increased knowledge and understanding of 3D systems can lead to future therapeutic/mitigation alternatives. This pillar is co-led by Dinesh R. Katti (NDSU) and Deniz Cakir (UND).
Explain it to me - What is deep learning?
Sanku Mallik
Professor of Pharmaceutical Sciences, North Dakota State University. Contact Sanku Mallik.
Archana Dhasarathy
Associate Professor of Biomedical Sciences, University of North Dakota. Contact Archana Dhasarathy.
Dinesh R. Katti
Jordan A. Enberg Presidential Professor of Civil and Environmental Engineering, North Dakota State University. Contact Dinesh R. Katti.
Julia Xiaojun Zhao
UND Chester Fritz Distinguished Professor of Chemistry, University of North Dakota. Contact Julia Xiaojun Zhao.
John C. Wilkinson
Associate Professor of Chemistry and Biochemistry, North Dakota State University. Contact John C. Wilkinson.
Deniz Cakir
Associate Professor of Physics & Astrophysics, University of North Dakota. Contact Deniz Cakir.
CCBSE Members
Austin Allard
Pre-Engineering Instructor, Turtle Mountain Community College. Contact Austin Allard.
Aaron Bergstrom
Advanced Cyberinfrastructure Manager, University of North Dakota. Contact Aaron Bergstrom.
Mikhail Bobylev
Professor of Chemistry, Minot State University. Contact Mikhail Bobylev.
Colin K. Combs
Chester Fritz Distinguished Professor and Chair of the Department of Biomedical Sciences at the University of North Dakota. Contact Colin K. Combs
Guodong Du
Professor of Chemistry, University of North Dakota. Contact Guodong Du.
Marcus Fries
Chair, Department of Mathematics & Computer Science & Associate Professor of Mathematics, Dickinson State University. Contact Marcus Fries.
Nicholas Galt
Assistant Professor of Science, Valley City State University. Contact Nicholas Galt.
Amanda Haage
Assistant Professor of Biomedical Sciences, University of North Dakota. Contact Amanda Haage.
Kerry Hartman
Academic Dean and Environmental Science Chair, Nueta Hidatsa Sahnish College. Contact Kerry Hartman.
Khang Hoang
Center for Computationally Assisted Science and Technology (CCAST) Research Scientist, North Dakota State University. Contact Khang Hoang.
Khwaja Hossain
Professor of Biology, Mayville State University. Contact Khwaja Hossain.
Svetlana Kilina
James A. Meier Associate Professor of Chemistry and Biochemistry, North Dakota State University. Contact Svetlana Kilina.
Jiha Kim
Assistant Professor of Biology, North Dakota State University. Contact Jiha Kim.
Michael Kjelland
Assistant Professor of Biology, Mayville State University. Contact Michael Kjelland
Trung Bao Le
Assistant Professor of Civil and Environmental Engineering, North Dakota State University. Contact Trung Bao Le.
Yen Lee Loh
Associate Professor of Physics & Astrophysics, University of North Dakota. Contact Yen Lee Loh.
Lu Liu
Assistant Professor of Computer Science, North Dakota State University. Contact Lu Liu.
Mike Parker
Professor of Pre-Engineering and Mathematics, Cankdeska Cikana Community College. Contact Mike Parker.
Mohiuddin Quadir
Associate Professor of Coatings and Polymeric Materials, North Dakota State University. Contact Mohiuddin Quadir.
Prakash Selvakumar
Assistant Professor, Department of Mechanical Engineering, North Dakota State University
Contact Prakash Selvakumar
Binglin Sui
Assistant Professor of Chemistry, University of North Dakota. Contact Binglin Sui.
Hilde van Gijssel
Professor of Science, Valley City State University. Contact Hilde van Gijssel.
Brent Voels
Professor of Science, Cankdeska Cikana Community College. Contact Brent Voels.
Wenjie Xia
Assistant Professor of Civil and Environmental Engineering, North Dakota State University. Contact Wenjie Xia.
Integration with PROSPER (PROmoting Sustainable Partnerships in Education and Research)
PROSPER, the broadening participation arm of ND-ACES, provides education and experiences designed to build a diverse workforce, enhance partnerships and collaborations with various stakeholders, and inform North Dakota’s residents. The four elements of PROSPER are: Education and Workforce Development, Broadening Participation, Partnerships and Collaborations, and Comunication and Dissemination.
The goals of the CCBSE research efforts/intellectual merit are enhanced via the simultaneous and linked broader impact efforts of the PROSPER team and will be achieved through the establishment of diverse and sustainable STEM education and professional development pathways and expanded bioscience partnerships and internships designed to enhance success in future federal funding and support the transformation of research into practical use via trained personnel and new products. PROSPER will also expand underserved and underrepresented participation, and inform the residents of North Dakota.
Three ND-ACES Mayville State University undergraduate student researchers in the newly created Integrated Cell Culture and Bio-imaging Laboratory at Mayville State University.
Broadening Participation
Broadening Participation supports American Indian students and other underserved groups along the biosciences pathway. The STEM content conveyed in the activities of this element correlate to the CCBSE research areas and align with this team’s objective to increase the participation of underrepresented and underserved groups in STEM across a variety of age groups from elementary school to Ph.D. faculty.
Education and Workforce Development
Education and Workforce Development Element strengthens ND’s bioscience/STEM ecosystem by building a diverse pool of competitive researchers, skilled workers, effective educators, and engaged students. Working in close conjunction with the CCBSE, this element supports faculty professional development, student training, and K-12 student bioscience, engineering, and computational exposure.
Partnerships and Collaborations
The Partnerships and Collaborations team builds research infrastructure and strengthens ND’s research competitiveness through industry partnerships and other collaborations. The team works with CCBSE researchers and industry relations personnel to collaborate on research partnerships using established research protocols.
Communication and Dissemination
The Communcation and Dissemination team is working toward the goal of developing an elevated public understanding of the economic impact of growing North Dakota’s bioscience sector through strategic research investments as a result of data-sharing, communication, and outreach. Communication and Dissemintaion integrates with CCBSE researcher and PROSPER teams to create engaging content for public dissemination.
Acknowledgment
The ND-ACES NSF Track-1 cooperative agreement is a federal-state partnership to manage a comprehensive research development plan. ND EPSCoR manages the Track-1 award. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation. Current funding is provided by the State of North Dakota and NSF EPSCoR Research Infrastructure Improvement Program Track-1 (RII Track-1) Cooperative Agreement Award OIA #1946202. The ND-ACES Principal Investigator (PI) and Project Director (PD) is Colleen Fitzgerald, Ph.D.; NDSU. The Co-PI is John Mihelich, Ph.D.; UND.